The conversion of acetoacetate to pyruvaldehyde.
نویسندگان
چکیده
The ozidative decarboxylation of acetoacetate to pyruvaldehyde is catalyzed by sheep heart extracts in the presence of O2 and Mn*+. The product was identified by spectral and chromatographic methods. From fractionation and inhibitor characteristics and the similarity of the catalytic activity to that of commercial myoglobin, it is concluded that the catalyst for the conversion in sheep heart extracts is myoglobin. A free radical mechanism which would account for the characteristics and requirements of the reaction is presented.
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ورودعنوان ژورنال:
- The Journal of biological chemistry
دوره 242 6 شماره
صفحات -
تاریخ انتشار 1967